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Key examples are the dual-specificity kinase DYRK1B, which participates in differentiation programs, and ERBB2/HER2, which activates pro-survival pathways through MAPK and PI3K/AKT

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The present review aims to elucidate the mechanisms by which copper ions are involved in cardiovascular diseases, summarize the impact of copper ion abnormalities on cardiovascular diseases and potential therapeutic approaches, and investigate whether modulating copper ion levels can ameliorate cardiovascular diseases

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